Sodium Citrate Buffer [0.01mol/L, pH 6.0] (Powder)

Sodium Citrate Buffer [0.01mol/L, pH 6.0] is a commonly used antigen retrieval solution, which can be used for paraformaldehyde, formaldehyde, or other aldehyde reagents to fix the antigen retrieval of samples such as paraffin sections, frozen sections, etc. It can effectively remove the cross-links between proteins caused by aldehyde fixation reagents, and fully expose the epitopes in the paraffin sections and other samples, thereby greatly improving the immunostaining effect.

Normally, paraffin sections need to be processed for antigen retrieval, while frozen sections need not be processed for antigen retrieval. Antigen retrieval can improve the immunostaining effect of paraffin sections, and can also improve the staining effect of frozen sections to varying degrees. When the immunostaining effect of frozen sections is not satisfactory, consider antigen retrieval.