Silica Coated Magnetic Beads

Overview

BIONEER’s Silica-coated Magnetic Beads are products with high-density silica (SiO₂) coating on the paramagnetic material, magnetite (iron(Ⅱ,Ⅲ) oxide, Fe₃O₄) surface. Depending on the size, Silica-coated Magnetic Beads are available as micrometer-sized AccuBead™ (1 - 5 μm) and nanometer-sized AccuNanoBead™ (200 nm/400 nm). All magnetic beads developed by BIONEER have pure magnetite as a core. Compared to other beads that use a polymer core, BIONEER’s magnetic beads have higher magnetic saturation, allowing for faster collection by a magnet. This enables more rapid separation and purification of target biomolecules. Additionally, BIONEER’s technology attaches more functional groups to the same surface area, allowing for capturing more target biomolecules with the same volume of magnetic beads, thus maximizing experimental efficiency. The hydroxyl groups of silica bind to sodium cations, which in turn bind to nucleic acids (DNA/RNA) in the presence of chaotropic salts (guanidine hydrochloride, guanidine thiocyanate, and sodium iodide). Utilizing this, Silica-coated Magnetic beads can isolate and purify nucleic acids from samples. This product magnetically isolates and purifies nucleic acids using the MagListo™ Magnetic Separation Rack (TM-1000, TM-1010, TM-1011, TM-1020, TM-1030) or other magnetic separation racks.

Features & Benefits

• A high magnetic density of 80.8 emu/g derived from a pure magnetite(Fe₃O₄) core
• Rapid magnetic capture within 5 seconds with a high magnetic density

• A high binding capacity of target molecules because of highly dense functional groups and smaller size
• Microplastics-free as no plastic cores like polystyrene

Applications

• Isolating and purifying Nucleic acids(DNA/RNA) from samples
• Isolating and purifying Plasmid DNA, genomic DNA, RNA, PCR product, etc.

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