JC-10 Mitochondrial Membrane Potential probe

JC-10 is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. Can detect cell, tissue, or purified mitochondrial membrane potential. When the mitochondrial membrane potential is high, JC-10 aggregates in the matrix of the mitochondria to form a polymer, which can produce red fluorescence; when the mitochondrial membrane potential is low, JC-10 cannot accumulate in the matrix of the mitochondria. At this time, JC-10 is a monomer, which can produce green fluorescence. In this way, it is very convenient to detect the change of mitochondrial membrane potential through the change of fluorescence color. The relative ratio of red and green fluorescence is commonly used to measure the ratio of mitochondrial depolarization.

Mol. Weight: ~600
Excitation: 510nm
Emission: 525nm